Cells are encapsulated within an alginate shell
1 second = 5 000 encapsulations
3D biomimetic environment
Encapsulation captured at 6000 frames per second (250x slow).
Cells are protected from mechanical stress
Large batch capacity
High reproducibility & low operational costs
Groundbreaking amplification factor (ask us ;))
Compatibility with 2D standard protocols
Easy 3D biology
Neurosphere (R=65μm) grown from neuronal stem cells differentiated into mature neurons within an alginate hollow capsule decorated with matrigel (staining for the neurite-specific marker beta3tubulin). Courtesy of Kevin Alessandri and Maxime Feyeux.
2018 : World’s first mature neuron graft to treat Parkinson’s disease. Collaboration between the Institute for Neurodegenerative Diseases (Erwan Bezard’s lab), the LP2N (Pierre Nassoy’s lab) and TreeFrog Therapeutics.
Ready-to-use graft format
Simplified cryopreservation & storage
On-demand dissolution of the alginate capsule
Co-development & licensing for cell therapies